Diogo Jota and Joao Felix both scored their first international goals in the second half before Bruno Petkovic pulled one back and Andre Silva then added a fourth.
If City win their next league game at Everton on March 31 that will set up a Manchester derby at City's Etihad Stadium where a win over their arch-rivals would secure the title.
A total of 18 people, including three soccer players, are to stand trial for match-fixing, a judge in Pamplona ruled on Thursday.
Netherlands capitalised on two England defensive mix-ups in extra time as they came from behind to win their Nations League semi-final 3-1.
Photos from the English Premier League matches played on Wednesday
Manchester City embark on a fifth Champions League campaign buoyant after a perfect start to their domestic season but still searching for the secret formula against Europe's top brass.
City are on top of the table with a one point advantage over Liverpool.
'We can work and fight for it' 'Yes, they had much more of the ball. Yes, they had that apparent control of the game but the biggest save is the double save of their goalkeeper and the biggest decision of the game is the unlucky decision of Michael (Oliver)'
Anger driving City to new heights, says City manager Manuel Pellegrini.
Ajax Amsterdam's Donny van de Beek grabbed an early goal to secure a precious 1-0 victory at Tottenham Hotspur in the first leg of their Champions League semi-final on Tuesday.
Chelsea begin their Premier League title defence against Swansea City on Saturday in the unusual position of heading into a new season having been significantly outspent by their rivals.
Real Madrid completed their pre-season tour of Australia with a crushing 4-1 friendly win over a depleted Manchester City in front of a record soccer crowd of 99,382 at the Melbourne Cricket Ground on Friday.
News of all that's transpired on and off the football field
IMAGES from the English Premier League matches played on Sunday
Kevin de Bruyne was hailed as playing football "on another level" by his manager Pep Guardiola after the Belgian maestro orchestrated another Manchester City symphony on Saturday.
Champions Chelsea have not enjoyed the best of starts at home this season and face their biggest test yet on Saturday with the visit of free-scoring leaders Manchester City.
Images from Saturday's matches in the Premier League.
Leicester City's Premier League title defence got off to a terrible start as they were beaten 2-1 at promoted Hull City, who shrugged off an injury crisis to shock the champions on the opening day of the new season on Saturday
Here are five talking points from the weekend's action:
Ranieri had recognised his future at the West London side was uncertain after Wednesday's stinging 2-0 defeat at Southampton.
Images from the English Premier League matches played on Saturday.
Liverpool manager Brendan Rodgers should explain to the fans his team selection against Real Madrid in Tuesday's Champions League Group B match, UEFA president Michel Platini said on Wednesday.
Manchester City survived a late grilling by Real Madrid thanks to goalkeeper Joe Hart to hold on for a 0-0 draw on Tuesday that keeps alive their hopes of reaching the Champions League final for the first time.
Here are six who could make the biggest impact in this season's English Premier League.
Images from the English Premier League matches played on Sunday
Manchester United held on for a goalless draw in a feisty derby with Manchester City after midfielder Marouane Fellaini was sent off for a headbutt in the Premier League clash at the Etihad Stadium on Thursday.
A summary of Saturday's action in the English Premier League.
Danny Welbeck, making his first appearance of the season as a late substitute, headed a stoppage-time winner to give Arsenal a 2-1 home win over league leaders Leicester City in the Premier League on Sunday.
IMAGES from the English Premier League matches played on Wednesday.
Title-chasing Tottenham Hotspur made hay in the sunshine as Son Heung-min scored twice in a 4-0 thrashing of Watford that closed the gap on Premier League leaders Chelsea to four points in Saturday's early kickoff.
Attack is the best form of defence for Manchester City boss Pep Guardiola.
For the first time in the seven-year history of the new Wembley, the arena was less than half full for an England international as 40,181 underwhelmed fans witnessed a familiar old diet of mostly turgid, uninspiring fare from Roy Hodgson's World Cup failures, enlivened mainly by the sparky contribution of Raheem Sterling.
News of all that's transpired on and off the football field.
Liverpool captain Steven Gerrard says Sunday's defeat to Arsenal in the FA Cup will not halt his team's momentum as they head into the crucial final stretch of the season.
Belgium beat England 2-0 in the World Cup third-place play-off on Saturday to secure their best ever finish at a World Cup and send Gareth Southgate's side home with a second straight loss.
Guardiola said City had plenty of options, with Gabriel Jesus the only main striker fit and ready but Ilkay Gundogan and Raheem Sterling are able to slot into the role.
Liverpool manager Brendan Rodgers was an immensely proud but competitive dad at Anfield on Sunday as his Premier League side overcame the FA Cup challenge of his son's third tier Oldham Athletic.
Manchester City are brimming with optimism with coach Manuel Pellegrini 'absolutely sure' of winning the Premier League title.
Jose Mourinho's side had paid lavish sums to bolster key areas by this time last year but, having claimed the title at a canter, the motto of this transfer window seems to be: if it ain't broke, don't fix it.
Sergio Aguero struck twice as Manchester City moved into second place in the Premier League, two points behind leaders Liverpool, with a 3-1 win at Bournemouth on Sunday. Just three weeks into the new season and last year's top two clubs are already perched at the top of the table.
